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STEROPEDIA

Anadrol - Oxymetholone

Basic Information

Common Name(s): Anadrol, A-Bombs, Oxy, Oxymetholone
Chemical Name: Oxymetholone
Class/Category: Anabolic-Androgenic Steroid (AAS)

Oxymetholone, commonly called Anadrol, is a powerhouse oral steroid famed for its ability to pack on muscle mass and strength rapidly. Originally developed to treat anemia and muscle-wasting conditions, it has become a go-to for bodybuilders looking to make quick, dramatic gains. However, its notable side effects, including water retention, blood pressure elevation, and liver toxicity, make it a compound that demands respect and careful management.

Administration & Dosage

Dosage Guidelines:

  • Beginners:

    • 25–50 mg per day. Even at these “lower” doses, users typically see substantial weight and strength gains.

  • Intermediate Users:

    • 50–100 mg per day. This is the “sweet spot” for most users, balancing results with tolerable side effects.

  • Advanced Users:

    • 100+ mg per day, though side effects (e.g., severe headaches, bloating) can escalate significantly.

Cycle Length:

  • 4–6 weeks maximum due to Anadrol’s hepatotoxicity (liver stress).
  • Splitting doses (morning/evening) helps maintain more stable blood levels, given its half-life of 8–9 hours.

Pro Tip: Always use liver support supplements like TUDCA, NAC, or Liv.52 and avoid alcohol or other liver-stressing substances.

Effects & Experience

Primary Intended Effects:

  1. Rapid Muscle Mass Gains:

    • Gains of 10–15 lbs (or more) are common within a few weeks, though some of this will be water retention.

  2. Dramatic Strength Increases:

    • A favorite for powerlifters looking for quick strength boosts.

  3. Enhanced Recovery & Endurance:

    • Users often report being able to train longer and recover faster.

Common Side Effects:

  • High Water Retention/Bloating:

    • Can lead to a “puffy” look and elevated blood pressure, though some find the added joint lubrication beneficial.

  • Estrogenic & Androgenic Issues:

    • Anadrol doesn’t aromatize directly but can still cause gyno, mood swings, and acne due to its estrogen-like activity.

  • Liver Toxicity:

    • One of the most hepatotoxic orals—regular monitoring of liver enzymes (AST/ALT) is crucial.

  • Appetite Suppression:

    • Higher doses may reduce hunger or cause stomach discomfort.

  • Blood Pressure & Cholesterol Shifts:

    • Anadrol can spike BP and worsen cholesterol profiles (increase LDL, lower HDL).

Time Course of Effects:

  • Onset: Strength and water retention typically appear within the first week.
  • Peak: Gains are most dramatic by weeks 2–3.
  • Duration: Anadrol is discontinued after 4–6 weeks to limit liver stress.
  • Post-Cycle: Expect some weight loss post-cycle as water retention subsides.

Pro Tip: Manage diet and sodium intake to minimize bloating and blood pressure issues.

Stacking

Common Stacks:

  • Anadrol + Testosterone Enanthate:

    • A classic bulking stack. Anadrol provides quick mass, while Testosterone serves as a stable anabolic base.

  • Anadrol + Deca-Durabolin:

    • A mass-gaining powerhouse, though expect increased water retention.

  • Anadrol + Trenbolone (Advanced Only):

    • Extreme strength and size gains, but requires experience due to severe side effects.

Stacking Guidelines:

  • Anadrol is usually used as a kickstart at the beginning of a cycle (4–6 weeks).
  • Rarely run alone—its suppressive nature requires a Testosterone base for hormonal support.
  • Avoid combining with other hepatotoxic orals like Dianabol to limit liver strain.

Pro Tip: Plan your stack and PCT to counteract Anadrol’s suppressive and hepatotoxic effects.

Safety & Risk Management

Major Risk Factors:

  1. Liver Toxicity:

    • Anadrol is among the most hepatotoxic steroids. Use TUDCA, NAC, and other liver support supplements.

  2. Blood Pressure:

    • Water retention and cardiovascular strain make BP monitoring essential. Adjust sodium intake and consider mild diuretics if needed.

  3. Cholesterol Changes:

    • Anadrol impacts lipid profiles—maintain a heart-healthy diet (rich in omega-3s) and regular cardiovascular activity.

  4. Hormonal Imbalance:

    • Anadrol is highly suppressive, so robust PCT is mandatory.

Warning Signs:

  • Headaches & Nosebleeds:

    • Often linked to high blood pressure.

  • Severe Bloating:

    • Adjust sodium and manage estrogen with an AI or SERM if symptoms persist.

  • Dark Urine or Jaundice:

    • Indicators of serious liver stress—discontinue immediately and seek medical attention.

Post Cycle Therapy (PCT)

Timing:

  • PCT timing depends on the longest-acting compound in your stack.
  • If Anadrol is used solo (not recommended), begin PCT 1–2 days after the last dose.

Protocol:

  • SERMs (e.g., Clomid, Nolvadex): Standard for restoring natural testosterone.
  • Liver Support: Continue liver health supplements during PCT.

Pro Tip: Bloodwork before and after the cycle is critical for assessing liver health, hormone levels, and overall recovery.

Final Word

Anadrol is a powerful mass-building steroid with the potential for jaw-dropping strength and size gains. However, it comes with significant risks, especially regarding liver toxicity, blood pressure, and hormonal suppression.

Key Takeaways:

  • Short Cycles Only: Limit usage to 4–6 weeks to protect your liver.
  • Plan for PCT: Anadrol’s suppressive nature demands a well-structured Post Cycle Therapy.
  • Monitor Health: Regularly check blood pressure, cholesterol, and liver enzymes.
  • Use Caution: Respect its potency—Anadrol isn’t for the faint-hearted or under-prepared.

When used responsibly, Anadrol can deliver explosive results, but preparation, monitoring, and careful dosing are essential. Lift big, but lift smart! 💪